Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria
2024
methylation
Capitella teleta; Dimorphilus gyrociliatus; Owenia fusiformis
DOI: 10.1186/s13059-024-03346-z
Source URL: Link
Species: Capitella teleta Dimorphilus gyrociliatus Owenia fusiformis
Authors: Kero Guynes; Luke A. Sarre; Allan M. Carrillo-Baltodano; Billie E. Davies; Lan Xu; Yan Liang; Francisco M. Martín-Zamora; Paul J. Hurd; Alex de Mendoza; José M. Martín-Durán
Abstract Excerpt: BACKGROUND: DNA methylation in the form of 5-methylcytosine (5mC) is the most abundant base modification in animals. However, 5mC levels vary widely across taxa. While vertebrate genomes are hypermethylated, in most invertebrates, 5mC concentrates on constantly and highly transc… Show more
Accessions: GSE250187 GitHub: ChemaMD/annelid5mC Zenodo: 10.5281/zenodo.12607960
| Order | Family | Species | Modality | Tissue | Stage |
|---|---|---|---|---|---|
| - | Capitellidae | Capitella teleta | methylation | developmental and aging time course | development / adult aging |
| - | Dinophilidae | Dimorphilus gyrociliatus | methylation | developmental and aging time course | development / adult aging |
| Sabellida | Oweniidae | Owenia fusiformis | methylation | developmental and aging time course | development / adult aging |